Our readers keep the lights on and my smoothie glass nicely filled. As an Amazon Associate, I earn from qualifying purchases.
Specs are compiled from manufacturer listings and verified buyer reviews and can change over time — please confirm the key details on the product page before buying.
That grease spot on your favorite shirt doesn’t have to be permanent. A dedicated degreaser is your best tool against oily stains from cooking, auto work, or any messy job — it breaks the oil down so your regular detergent can wash it away completely. But not all degreasers are safe for fabric, and picking the wrong one can set a stain or damage the fibers.
I’m Mohammad Maruf — the founder and writer behind WellFizz. This guide is built by comparing the manufacturers’ published specifications and the patterns across verified customer reviews, so you get each pick’s real strengths and trade-offs instead of marketing spin.
We’ve sorted through the options to find the best clothing degreaser for your laundry, if you need a heavy-duty soak for mechanic’s coveralls or a gentle spray for a kitchen apron.
Our Picks at a Glance
How To Choose The Best Clothing Degreaser
Choosing the right degreaser for clothes depends on formula type, concentration, and fabric compatibility. You need a formula that cuts oil without stripping dye or leaving a residue behind. Here is what matters most.
Enzyme vs. Solvent Formulas
An enzyme-based prewash (like Soilove) uses proteins that latch onto organic stains and lift them out. These are gentle on fabric and effective on food grease, blood, and grass. Solvent-based products (like Orange-Sol De-Solv-It) dissolve sticky or petroleum-based messes like tar, wax, or heavy machine oil. Choose based on what you are cleaning — cooking grease or garage grime.
Concentration and Dilution
A concentrated formula (like Fuller Brush Fulsol) often delivers more cleaning power per ounce. You can use it full-strength on a tough stain or dilute it for lighter loads. A ready-to-use spray is convenient for spot treatment, but a concentrate usually gives you more value and control over the strength you need.
Fabric and Machine Compatibility
Check that the degreaser is safe for colorfast fabrics and works in both hot and cold water. Most enzyme prewashes are fine for HE washers. If you have sensitive skin, look for fragrance-free, non-toxic, or biodegradable options that rinse clean without leaving harsh chemical traces in your clothes.
Quick Comparison
| Model | Best For | Formula Type | Size / Yield | Key Feature | Amazon |
|---|---|---|---|---|---|
| Soilove 128 oz Refill★ Best Overall | Everyday laundry stains | Enzyme Prewash | 128 oz | Triple-acting lift | Amazon |
| Oil Eater 1 GallonPro Grade | Heavy grease + multi-surface | Solvent Concentrate | 1 gallon | USDA food-facility safe | Amazon |
| Grease Relief 18 oz SprayQuick Fix | Kitchen grease + spot treatment | All-Purpose Spray | 18 oz | Non-toxic, biodegradable | Amazon |
| Orange-Sol De-Solv-It | Stubborn residue + wax | Citrus Solvent | 12 oz | Essential oils, safe on skin | Amazon |
| Truly Free Heavy Duty Degreaser | Fragrance-free household cleaning | Plant-based Concentrate | 16 oz bottle + 2 fills | Refillable, plant-powered | Amazon |
| LA’s Awesome + Soilove Combo | Versatile home + laundry | Enzyme + All-Purpose | 24oz spray + 64oz refill | 2-in-1 bundle value | Amazon |
| Soilove 6-Pack (16 oz) | Multi-bottle laundry staple | Enzyme Prewash | 6 x 16 oz | Value size, USA made | Amazon |
| Fuller Brush 2X Fulsol | Concentrated home + laundry | Concentrate Cleaner | 1 quart (makes 30 gal) | Double power, safe on most surfaces | Amazon |
| Fuller Brush Fulsol 1 Gal | Maximum heavy-duty value | Concentrate Cleaner | 1 gallon (makes 60 gal) | Lemon scent, degreasing power | Amazon |
In‑Depth Reviews
1. Soilove Stain Remover for Clothes, 128 oz Triple-Acting Laundry Prewash
Our pick — over 4.5★ from 500+ verified ratings; the strongest balance of quality and price.
The crowd favorite that lifts every stain you throw at it, from blood to barbecue sauce.
Soilove uses a triple-acting enzyme formula that clings to fabric fibers, penetrates deep into the stain, and lifts it out before washing. You can use it in hot or cold water, and it is safe for both HE and standard machines. At 128 ounces, this refill bottle is the most economical way to keep a spray bottle full — you are getting a massive 8 pounds of product that handles grease, grass, food, coffee, and wine with equal confidence.
Owners consistently praise its stain-removal power — the most-discussed aspect by far. As buyers put it: “I have been able to get out every stain – it hasn’t failed me yet.” Even old stains that have already been through the dryer come out on a second pass. The only honest caveat is the size: this jug is heavy (8 pounds) and you will need your own spray bottle for spot-treating. That is a minor trade-off for the sheer value and the 4.8-star reputation across over 500 owners.
If you want one degreaser that tackles the whole family’s laundry without fussing over diluted ratios or mixing, this is it.
What Wins People Over
- Enzyme formula works on fresh and set-in stains
- Huge 128 oz refill reduces plastic waste and per-load cost
- Safe for colorfast fabrics in any water temperature
The Practical Trade-Off
- Heavy jug (8 pounds) requires your own spray bottle for spot treatment
- Some find it less effective on petroleum-based stains than solvent degreasers
Grab it for: anyone who wants a proven, cost-effective laundry prewash that handles everyday grease and stains without guessing.
Think twice if: you need a general-purpose household cleaner for surfaces — this is strictly a laundry prewash.
2. Oil Eater Original 1 Gallon Cleaner, Degreaser
The industrial-strength degreaser that is food-service safe and works on everything from floors to laundry.
Oil Eater is a professional-grade concentrate that dissolves grease, oil, and dirt from any washable surface. It is USDA approved for use in food service facilities (ratings A1, A4, A8), so you can trust it on kitchen gear without worrying about harsh residues. The formula is biodegradable and noncorrosive — no harsh solvents. At 8.5 pounds for a gallon, it is a heavy bottle but the concentrated power means you can dilute it. Get a 10.7x size advantage compared to a small 12 oz spray like the Orange-Sol De-Solv-It.
Owners who push it hardest confirm it cuts through serious grime. One buyer described how it “cuts through kerosene-based coolant residue from a fire on break room floor” when used diluted in a spray mop. Others use it undiluted on guns, chainsaw pitch, and even old wood glue. It works as a laundry prewash too — just spot-treat the oil mark before the wash.
The trade-off is its versatility: it is not a dedicated laundry prewash, so you may need to experiment with your dilution ratio. The crowd-sourced wisdom is to start at a 3:1 or 1:1 mix for laundry stains rather than the label’s 10:1 suggestion.
Why It Stands Out
- USDA approved for food facilities — safe and trusted
- Biodegradable and noncorrosive formula
- Ultra-concentrated: one bottle goes a long way
Who Should Pause
- Not a dedicated laundry product — dilution ratios take trial
- Heavy bottle (8.5 pounds) is not meant for spot-treated spray bottles
Reach for it if: you want one cleaner that works on clothes, floors, grills, and garage messes without buying separate products.
skip it if: you only need a simple spray-and-wash laundry prewash — this requires mixing.
3. Degreaser and Laundry Stain Remover (18 oz) – Grease Relief
A grab-and-go spray that pulls double duty on kitchen grime and laundry grease spots.
Grease Relief combines heavy-duty cleaning power with a non-toxic, biodegradable formula. It is fume-free and dye-free, making it a good choice if you are sensitive to strong chemical smells. The 18-ounce bottle works as an all-purpose degreaser for stove tops, ovens, and grills, then pulls duty as a laundry spot treater. Spray it on a grease stain, let it sit, and toss it in the wash.
Grease removal is the top positive aspect, winning over most owners. Buyers report it gets out “ALL stains in clothing” and even handles tricky spots like Aquaphor after a second treatment. As buyers put it: “Second time around I repeated the same process and the stain was gone!!” A recurring physical complaint is that the spray bottle can leak during shipping, so be careful opening the package.
It is a hair smaller than some competitors at 18 oz, but the ready-to-use convenience means zero mixing or measuring. That makes it a solid entry-level pick for someone who wants one product for the kitchen and the laundry room.
Best spot for it: if you cook often and need a single spray that handles both greasy pans and apron stains — no mixing required.
The honest catch: bottle leakage during transit is a known complaint; open over a sink or towel.
4. Orange-Sol De-Solv-It Citrus Solution 12 oz
A citrus-based solvent that dissolves sticky residue and tough stains without damaging fabric.
De-Solv-It is not your average laundry spray. It is a citrus solvent that breaks down permanent residue, candle wax, ink, paint, grease, and tar from any surface — including clothes, upholstery, wood, glass, and metal. The formula includes essential oils, vitamins, and aloe, making it gentle on skin and lungs. The 12-ounce bottle is small compared to the 128-ounce Soilove refill (a 10.7x size gap), but this is intentional: a little goes a long way on tough spots.
Owners love its effectiveness across surfaces — the top positive aspect by a wide margin. It removes sticky glue residue and labels from jars, gets candle wax out of fabric church pews, and cleans working men’s clothes of grease. As buyers put it: “I have yet to see a stain it can’t tackle.” The scent is where opinions split — some find it pleasant while others compare it to WD-40, so try it on a small area first if you are sensitive to smells.
This is the pick for ultra-tough, non-greasy messes like tar or wax that an enzyme prewash won’t touch. It is also safe on hard surfaces, making it a true multi-tasker.
Best for: sticky glue, candle wax, and petroleum-based stains that standard laundry spray cannot crack.
Consider the size: at 12 oz it disappears fast if you use it as your main laundry spray — pair it with a bulk refill for everyday stains.
5. Truly Free Heavy Duty Degreaser – Plant-Powered, Refillable Kit
A plant-powered degreaser with zero fragrance — built for sensitive noses and eco-friendly homes.
Truly Free breaks away from the solvent-heavy norm. Its formula is powered by plant-based ingredients with no synthetic fragrances or harsh chemicals, making it a strong option for households with sensitive skin or a preference for green cleaning. The kit includes a reusable 16-ounce spray bottle and two small refill packs (3 fl oz each) that you mix with water. Spray it on oven doors, cooktops, or grease stains on clothes, let it sit, and wipe away.
The feedback is split: owners who love it call it “great” and say it “wipes out the grease easily” with no smell at all. But a significant group finds it requires serious scrubbing on heavy buildup, especially caked-on stains. As some owners put it, it works “great on newer stains, not great on caked on ones.” At its price point, it lands in the premium territory, so the value comes from avoiding chemical exposure rather than raw degreasing power.
This is the degreaser to reach for when you want to clean your oven and pre-treat a shirt in the same session without breathing harsh fumes.
The Green Appeal
- Plant-powered, fragrance-free, safe for sensitive skin
- Refillable bottle reduces single-use plastic waste
- No harsh chemical smell during use
Performance Check
- Requires more scrubbing on baked-on or old stains
- Premium price for a smaller total volume of cleaner
Best fit: eco-conscious households and anyone who needs a fragrance-free degreaser for kitchen and laundry spot treatment.
Not for you if: you need heavy-duty, one-pass power on thick, caked-on grease — you will be scrubbing.
6. LA’s Totally Awesome All-Purpose Cleaner Combo + Soilove 16oz (Pack of 2)
Two proven products in one bundle — a multi-surface cleaner and a dedicated laundry stain remover.
This combo pairs LA’s Totally Awesome All-Purpose Cleaner (a 24-ounce spray plus a 64-ounce refill) with two 16-ounce bottles of Soilove Laundry Stain Remover. It is designed for households that want both a general degreaser for counters, floors, and auto interiors, and an enzyme prewash for laundry. LA’s cleaner is bleach-free, ammonia-free, and phosphate-free, while Soilove tackles blood, grass, food, ink, and grease on colorfast fabrics.
Early owners are happy with the value — they report the spot treater works well on work clothes and that the bundle “does the job” without fuss. As one buyer put it: “This Awesome is awesome! Some strong stuff.” The bundle is a convenient way to get both products in one order, especially if you are already a fan of LA’s Totally Awesome and want to try Soilove.
The only thing to note is that the kit is relatively new on Amazon (November 2024), so the long-term review base is still small. But both individual products are well-established.
Perfect if: you like the convenience of a single purchase that covers kitchen counters, car interiors, and laundry stains.
Consider this: if you already own an all-purpose cleaner, buying Soilove alone (product 1) might be simpler and cheaper.
7. Soilove Laundry Stain Remover Liquid – 6 Bottles (16 oz Each)
The same beloved enzyme formula in a six-pack — perfect for multiple laundry baskets or giving extras away.
This is the same Soilove enzyme prewash that earned the top spot, now in a six-bottle value pack of 16-ounce spray bottles. Each bottle uses the triple-action formula that clings, penetrates, and lifts stains including blood, grease, grass, makeup, ink, red wine, and food spills. It is safe for all colorfast fabrics and works in any water temperature. The spray bottle design means you can treat a stain immediately and let it sit — even wash it later without losing effectiveness.
Owner consensus is overwhelmingly positive. Stain removal is the most-discussed positive aspect, with 130 mentions. Long-time users have been buying Soilove for over 20 years, and they say it “gets out everything including yellow sweat stains in the pits of shirts.” As buyers put it: “We’ve been using this for years and years… it will get out everything every time.” The only recurring negative is leakage — a small number of bottles arrive with a popped nozzle or cap, so inspect the package when it arrives.
If you are already a Soilove convert, this six-pack is the most economical way to keep a bottle in every bathroom, laundry room, and gym bag.
The Proven Track Record
- Same powerful enzyme formula with a 20-year following
- Six bottles mean you can stash one everywhere you need it
- No scrubbing needed — spray, let sit, wash
The Small Annoyance
- Occasional bottle leakage or popped nozzle in transit
- 16 oz per bottle goes fast in a busy household
Reach for this if: you already love Soilove and want to stock up for the year or share with family.
pass on it if: you prefer a single large refill (128 oz) to reduce plastic waste — that is the more eco-friendly route.
8. Fuller Brush 2X Power Fulsol Degreaser – 1 Quart
A concentrated quart that turns into 30 gallons of cleaning power — a serious value play.
Fuller Brush’s Fulsol 2X Power is a heavy-duty concentrate that cuts grease, oil, dirt, grass stains, ink, and glue from practically any surface. One quart makes up to 30 gallons of cleaner, which is enormous value for a household that goes through degreaser quickly. The formula is biodegradable, phosphate-free, and safe for septic systems. It works on tile, glass, woodwork, painted surfaces, and all washable fabrics — including laundry. A little goes a long way: owners say a small amount lasts long on greasy pots, pans, and stovetop splatters.
The Fuller Brush brand carries weight with loyal buyers — some families have used it for over 80 years. The positive reviews highlight how one application cuts through grease on stove vents, and it works “extremely well on removing grease on stove/vent.” It is also effective on oily clothes stains when used as a pre-spotter.
The main consideration is that it is not a dedicated laundry product. You will need to experiment with dilution ratios for clothing versus hard surfaces. Also, the quart bottle is small but heavy (2.3 pounds) — it is designed to be mixed, not sprayed directly.
Ideal for: anyone who wants a super-concentrated, multi-surface degreaser for the whole house — from laundry to grills to tile.
Keep in mind: you will need your own spray bottle and a few test runs to find the right dilution for laundry stains.
9. Fuller Brush Fulsol Heavy-Duty Degreaser 1 Gallon – Lemon Scent
The big-daddy gallon that makes 60 gallons of cleaner — buy once, clean for a year.
This is the most concentrated option on the list. A single 8.64-pound gallon of Fuller Brush Fulsol (lemon-scented version) dilutes to an incredible 60 gallons of cleaning solution. It is a super-concentrated, biodegradable, phosphate-free all-purpose cleaner that removes grease, oil, dirt, and grime from tile, glass, woodwork, grills, and laundry. Use it full-strength on the worst stains or dilute for lighter everyday cleaning.
Owners with demanding cleaning loads confirm it is “the BEST Degreaser I’ve ever used.” It removes ink, grease, and car grease from clothing even after a trip through the washer and dryer. Farmers and mechanics rely on it: they rub it into grease stains, let it set, and wash in hot water — it “never fails on grease stains.” The lemon scent is a bonus over the 2X Power version if you prefer a fresher smell while cleaning.
The up-front cost is the highest on this list, but the per-gallon-of-use cost is by far the lowest. If you have a large family or heavy grease exposure (farming, auto work, restaurant uniforms), this is the most economical long-term choice. The only warning is to follow dilution directions — it can remove paint if used full-strength on the wrong surface.
The Heavyweight Appeal
- Makes a whopping 60 gallons of cleaner from one jug
- Works on grease stains that have been through the dryer
- Pleasant lemon scent compared to most industrial degreasers
Consider Before Buying
- High initial investment — only worth it if you clean heavily
- Must dilute for most uses; strong undiluted can strip paint
Best for: farms, workshops, and large households where grease is a daily battle and value per gallon is the priority.
Too much if: you just want a small spray for occasional laundry stains — stick to a ready-to-use product.
Understanding the Specs
Enzyme vs. Solvent Formulas
An enzyme prewash uses proteins that digest organic stains like food grease, blood, and grass. These formulas cling to fabric fibers and lift the stain out during the wash cycle. A solvent degreaser (like citrus or petroleum-based) dissolves non-organic messes such as tar, wax, ink, and heavy machine oil. For cooking grease, an enzyme formula is usually enough. For garage or workshop grime, you might need a solvent.
Concentration and Dilution Ratio
Concentrated degreasers (like Fuller Brush Fulsol) save money over time because you mix them with water yourself. A quart that makes 30 gallons costs more upfront but costs less per use than a ready-to-use spray. The trade-off is convenience: you need a spray bottle, and you have to measure and mix. Ready-to-use sprays cost more per ounce but are simpler for quick spot treatments.
Fabric and Water Temperature Compatibility
Most clothing degreasers work in both hot and cold water, and are safe for colorfast fabrics and high-efficiency (HE) washing machines. If you have sensitive skin, look for a fragrance-free, non-toxic, or biodegradable label. Always test on an inconspicuous area first — especially with solvent-based formulas that can set some stains or affect certain dyes.
Bottle Size and Value
A 128-ounce refill jug (like the Soilove) gives you the most degreaser for the price, but you need your own spray bottle. A 16-ounce spray bottle is convenient for spot treatment but runs out fast in a busy household. Multi-packs offer convenience but produce more plastic waste. The best choice depends on how often you do laundry and whether you prefer refilling or grab-and-go convenience.
FAQ
Can I use any degreaser on any fabric?
How do I treat a grease stain before washing?
What is the difference between a degreaser and a regular stain remover?
Are degreasers safe for high-efficiency (HE) washing machines?
How do I remove an old grease stain that has already been dried?
What is the best degreaser for mechanic or heavy grease stains?
Can I use a degreaser on upholstery or couches?
How long can I let a degreaser sit on fabric?
Will a degreaser remove sweat stains from white shirts?
Is citrus-based or enzyme-based degreasing better for laundry?
Final Thoughts: The Verdict
For most buyers, the clothing degreaser winner is the Soilove 128 oz Refill because it combines a proven enzyme formula, massive value, and the highest owner satisfaction across thousands of ratings. If you prefer a spray-and-go bottle for the kitchen and laundry alike, the Grease Relief 18 oz Spray is a solid mid-range choice. And for the heaviest, most stubborn grease — from auto work to farm life — the Fuller Brush Fulsol 1 Gallon offers the best long-term value with its super-concentrated, 60-gallon yield.
How We Picked
We do not accept paid placement. Every pick is matched to a real buyer and a real use-case; we do not hands-on test units.
Sources & Methodology
Specifications: manufacturer listings and product documentation. Review insights: verified customer reviews, as of July 2026. Pricing: not shown on this page (it changes often); check the current price via the retailer link.
As an Amazon Associate, WellFizz earns from qualifying purchases. This does not affect which products we feature.
Related Guides
Mo Maruf
I created WellFizz to bridge the gap between vague wellness advice and actionable solutions. My mission is simple: to decode the research and give you practical tools you can actually use.
Beyond the data, I am a passionate traveler. I believe that stepping away from the screen to explore new environments is essential for mental clarity and physical vitality.